Therapy for NASH Cirrhosis is a Distant Hope

NASH is a chronic liver disorder that results in progressive fibrosis, ultimately culminating in some patients in liver cirrhosis. In cirrhosis, the fibrotic scar tissue distorts the normal liver...
Learn More

Is Gilead’s Selonsertib for NASH Dead?

Title: Is Gilead’s Selonsertib for NASH Dead? Author: Peter G. Traber, MD Date: 02/12/2019 Introduction The search for an effective therapy for NASH with advanced fibrosis/cirrhosis suffered a major...
Learn More

Orkambi UK - Sound and Fury

By Anthony Walker, PhD, Managing Partner There’s a lot of sound and fury about Orkambi in the UK. Following a rejection from NICE, Vertex and NHS England have not been able to reach terms and the...
Learn More

Why Every Biotech Needs a Scouting Function

Alacrita frequently supports companies with their search and evaluation activities. Our scouting support is often structured to integrate with a client’s internal efforts to generate a flow of new...
Learn More

microRNAs as drug targets

microRNAs as drug targets Saadia Basharat, PhD, Senior Consultant microRNAs (miRNA) are small noncoding RNAs that regulate the expression of multiple target genes by either blocking the translation...
Learn More

Infographic: Britain crashes out of favor with US pharmaceutical executives

Britain crashes out of favor with US pharmaceutical executives The biotech industry is a pillar of the knowledge economy, with governments around the world investing heavily to attract capital and...
Learn More

NASH Surprises and Interpretation of Clinical Trials

Title: NASH Surprises and Interpretation of Clinical Trials Author: Peter G. Traber, MD Introduction 2019 will usher in a new chapter in NASH drug development with data reported on the first phase 3...
Learn More

Pharma Defying Gravity – How Much Longer?

Anthony Walker, PhD, Managing Partner, Alacrita Consulting
Learn More

Routes to European Commercialisation in Europe

Title: Routes to Commercialisation in Europe Author: Anna Casse, Managing Partner Abstract In the past it was not extraordinary for US biotech companies to develop drugs in the US and to launch them...
Learn More

Agencies Clarify NASH Endpoints—But Don’t Harmonize

Title: Agencies Clarify NASH Endpoints—But Don’t Harmonize Author: Peter G. Traber, MD The FDA and EMA have recently published very similar clinical trial endpoints for pre-cirrhotic NASH, with one...
Learn More

Industry Strategies for NASH Combination Therapies

Introduction: Many have commented that drug combinations represent the future of NASH therapeutics. As indicated by Pfizer’s recent announcement, large pharma companies are putting efforts toward the...
Learn More

Is Rapid Reversal of Liver Fibrosis Possible?

Title: Is Rapid Reversal of Liver Fibrosis Possible? Author: Peter G. Traber Introduction Treatment of liver fibrosis is a major focus of drug development with multiple companies examining a variety...
Learn More
Previous
1 ... 2 3 4 5 6
Next

Need biotech consulting support? We can help.

Contact us today to learn how our pharma & biotech consulting expertise can serve your project.

Contact us

Explore our biotech & life science consulting services

© 2009-24 Alacrita Holdings Limited  |   Pharma & Biotech Consulting

Alacrita Consulting 
2 Royal College St
London, UK
NW1 0NH

Registered in England & Wales.
No. 10530608


One Broadway
Floor 14
Cambridge, MA 02142

Registered in Massachusetts.